About BioCell Innovations
BioCell Innovations Pte Ltd is a Singapore-based company with the primary objective to bring cell and gene therapy to patients-in-need, offering them effective and personalized treatment options. Through extensive research and development, we have developed a range of cutting-edge technologies and platforms to drive this mission forward. One of our core technological advancements lies in our novel cell manufacture process, which aims to reduce potential adverse events associated with cytokine release syndrome (abbreviated as CRS). CRS is a common side effect of chimeric antigen receptor (CAR)-T cell therapy, leading to varying degrees of toxicity and can be fatal to patients. By coupling this innovative method with in-house developed CAR lentiviral vectors (LVs) such as humanized CD19 CAR LVs, we can minimize the occurrence and severity of CRS while maintaining robust anti-tumour efficacy of CAR-T cells. This will significantly improve patient safety and treatment outcomes. This process sets us apart and positions BioCell Innovations Pte Ltd as a frontrunner in the development of safe and effective cell-based therapies. Furthermore, we have on-going development of in-house CAR constructs for both autologous and allogenic T cells development, and this plan is also facilitated through collaboration with key partners in relevant industries and hospitals.
Fostering Collaborations
Vector design construction
- Optimizing Process Development
- CAR-T cell characterization
- CAR-T cell Function Monitoring
- Support clinical CAR-T administration
- Project Management
Our Projects
Explore the impactful projects that exemplify our commitment to pushing the boundaries of cell and gene therapies
We’ll Ensure You Always Get The Best Result
Cutting-Edge Innovation
Revolutionary cell and gene therapies driven by cutting-edge technologies
Patient Safety
First
Your Safety Matters: Opt for BioCells Innovations to prioritize patient safety
Proven Efficacy in CAR-T Therapy
Enhanced CAR-T Effectiveness: You can trust us for our expertise in CAR-T therapy
Collaborative Progress
Partner with BioCells for our commitment to collaborative progress.
Meet Our laboratory Experts
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- News
Memorandum of Understanding & Collaboration Agreement Signing Ceremony
BioCell Innovations Pte Ltd has recently signed a Memorandum of Understanding with Thermo Fisher Scientific Pte Ltd (a subsidiary of Thermo Fisher Scientific Inc) aiming to optimize a closed process for the clinical manufacturing of lentiviral-based immunotherapies within the Asia-Pacific region. We are excited to collaborate and to support new opportunities by bringing together BioCell […]
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- Our Capabilities
Collaborations and Partnerships
Currently, all FDA-approved anti-CD19 CAR T-cell therapies are developed using a single-chain variable fragment (scFv) derived from murine FMC63. However, the presence of non-human (murine) scFv may induce human anti-mouse antibody (HAMA) response which would subsequently affect the persistency of CAR T cells in vivo1. Patients with relapsed or refractory acute lymphoblastic leukemia that had […]
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- Our Capabilities
Personalized Cell and Gene Therapy
In the recent decade, medicine has experienced remarkable transformations in disease treatment, with personalized therapies emerging as pivotal agents of change. These therapies take into account each patient’s unique characteristics, leading to more effective disease management. The primary catalyst for this advancement stemmed from complex acquired illnesses such as cancer. A breakthrough was the development […]